The birth of his first child prompts an adopted man to begin a search for his own biological parents. However, he has to contend with several cases of mistaken identity, his adoptive parents' feeling of rejection and his own attraction to a psychology student helping him in his quest. Comedy, starring Ben Stiller, Patricia Arquette, Mary Tyler Moore, Tea Leoni, George Segal, Alan Alda and Lily Tomlin.

Adopted as a child, new father Mel Colpin decides he cannot name his son until he knows his birth parents, and determines to make a cross-country quest to find them. Accompanied by his wife, Nancy, and an inept yet gorgeous adoption agent, Tina, he departs on an epic road trip that quickly devolves into a farce of mistaken identities, wrong turns, and overzealous and love-struck ATF agents.